Cytokeratin 9,细胞角蛋白9抗体

产品编号HZ-8478R
英文名称Cytokeratin 9
中文名称细胞角蛋白9抗体
别 名CK 9; CK-9; Cytokeratin 9; Cytokeratin-9; Cytokeratin9; EPPK; K1C9_HUMAN; K9; Keratin 9; Keratin; Keratin type I cytoskeletal 9; Keratin-9; Keratin9; KRT 9; KRT9; type I cytoskeletal 9.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Sheep,
Cytokeratin 9,细胞角蛋白9抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量62kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Cytokeratin 9
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cytokeratin 9,细胞角蛋白9抗体PubMedPubMed
产品介绍background:
This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008]

Function:
May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.

Tissue Specificity:
Expressed in the terminally differentiated epidermis of palms and soles.

DISEASE:
Defects in KRT9 are a cause of palmoplantar keratoderma epidermolytic (EPPK) [MIM:144200]; also abbreviated as EHPPK. EPPK is a dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present with knuckle pads, thick pads of skin appearing over the proximal phalangeal joints.

Similarity:
Belongs to the intermediate filament family.

Gene ID:
3857

Database links:
Entrez Gene: 3857 Human
Omim: 607606 Human
SwissProt: P35527 Human
Unigene: 654569 Human

Cytokeratin 9,细胞角蛋白9抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.