RAD51 purified MaxPab mouse polyclonal antibody (B01P)
产品名称: RAD51 purified MaxPab mouse polyclonal antibody (B01P)
英文名称: RAD51 purified MaxPab mouse polyclonal antibody (B01P)
产品编号: H00005888-B01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human RAD51 protein.
- Immunogen:
- RAD51 (NP_002866.2, 1 a.a. ~ 339 a.a) full-length human protein.
- Sequence:
- MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
- Download
- Applications
- Western Blot (Tissue lysate)
- RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in human colon.
- Protocol Download
- Western Blot (Cell lysate)
- RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in PC-12.
- Protocol Download
- Western Blot (Cell lysate)
- RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in Raw 264.7.
- Protocol Download
- Western Blot (Cell lysate)
- RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in Jurkat.
- Protocol Download
- Western Blot (Cell lysate)
- RAD51 MaxPab polyclonal antibody. Western Blot analysis of RAD51 expression in NIH/3T3.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of RAD51 expression in transfected 293T cell line (H00005888-T01) by RAD51 MaxPab polyclonal antibody.
Lane 1: RAD51 transfected lysate(37.29 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Immunoperoxidase of purified MaxPab antibody to RAD51 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
- Protocol Download
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Transfected lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Detection Antibody
- Entrez GeneID:
- 5888
- GeneBank Accession#:
- NM_002875
- Protein Accession#:
- NP_002866.2
- Gene Name:
- RAD51
- Gene Alias:
- BRCC5,HRAD51,HsRad51,HsT16930,RAD51A,RECA
- Gene Description:
- RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- BRCA1/BRCA2-containing complex, subunit 5,DNA repair protein RAD51 homolog 1,RAD51 homolog protein,RAD51, S.cerevisiae, homolog of, A,RecA, E. coli, homolog of,RecA-like protein,recombination protein A
- Related Disease
- Acute Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Ductal
- Carcinoma, Ductal, Breast
- Carcinoma, Intraductal, Noninfiltrating
- Carcinoma, Lobular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Papillary
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Chromosome Aberrations
- Colorectal Neoplasms
- DNA Damage
- DNA Repair-Deficiency Disorders