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上海信裕生物科技有限公司
BBS8抗体

BBS8抗体

商家询价

产品名称: BBS8抗体

英文名称: BBS8Antibody

产品编号: XY12505-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 BBS8抗体

Applications
In-house applications ELISA, WB, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 12505-1-AP;mouse testis tissuemouse testis tissue were subjected to SDS PAGE followed by western blot with 12505-1-AP(TTC8 antibody) at dilution of 1:300
  • 12505-1-AP;HeLa cellsIP Result of anti-TTC8 (IP:12505-1-AP, 3ug; Detection:12505-1-AP 1:400) with HeLa cells lysate 2000ug.
Positive WB detected in Mouse testis tissue, human lung tissue, NIH/3T3 cells
Positive IP detected in HeLa cells
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
 BBS8抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information BBS8抗体
Immunogen BBS8 fusion protein ag3186 Full name Tetratricopeptide repeat domain 8
Calculated molecular
weight
531aa,60 kDa Observed molecular 
weight
50-52 kDa
GenBank accession 
number
BC026351 Gene ID (NCBI) 123016
Gene symbol TTC8 Synonyms BBS8, TPR repeat protein 8, TTC8
Background

BBS8 (also known as TTC8) is a subunit of BBSome complex which is necessary for ciliary membrane biogenesis. BBS8 localizes specifically to ciliated structures, such as the connecting cilium of the retina and columnar epithelial cells in the lung. Defects in BBS8 cause Bardet-Biedl syndrome type 8 (BBS8), an genetic disorder characterised by retinal degeneration, obesity, polydactyly, cognitive impairment and kidney failure. BBS8 generates two alternatively spliced isoforms. Western blot analysis using this antibody detected a major band around 60 kD in lung tissue. BBS8抗体

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