GADD45A抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
GADD45A抗体

GADD45A抗体

商家询价

产品名称： GADD45A抗体

英文名称： GADD45AAntibody

产品编号： XY13747-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 GADD45A抗体

Applications
In-house applications ELISA, WB, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 13747-1-AP;PC-13 cellsPC-13 cells were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:600
  • 13747-1-AP;K-562 cellsIP Result of anti-GADD45A (IP:13747-1-AP, 4ug; Detection:13747-1-AP 1:500) with K-562 cells lysate 3200ug.
Positive WB detected in PC-13 cells, A549 cells, COLO 320 cells, K-562 cells, mouse lung tissue, mouse spleen tissue, rat lung tissue
Positive IP detected in K-562 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
GADD45A抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen GADD45A fusion protein ag4687 Full name Growth arrest and DNA-damage-inducible, alpha
Calculated molecular
weight		 165aa,18 kDa Observed molecular 
weight		 18 kDa or 36 kDa
GenBank accession 
number		 BC011757 Gene ID (NCBI) 1647
Gene symbol GADD45A Synonyms DDIT 1, DDIT1, GADD45, GADD45A
BackgroundGADD45A抗体

GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~36 kDa) and Mono (~18 kDa) forms (PMID:11498536).GADD45A抗体

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