CENPA polyclonal antibody
产品名称： CENPA polyclonal antibody
英文名称： CENPA polyclonal antibody
产品编号： PAB18324
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CENPA.
- Immunogen:
- A synthetic peptide corresponding to human CENPA.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This antibody is specific to CENPA.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M.Cell. 2006 Nov 3;127(3):635-48.
- 2.
- The human CENP-A centromeric nucleosome-associated complex.
Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR 3rd, Cleveland DW.Nat Cell Biol. 2006 May;8(5):458-69. Epub 2006 Apr 16.
- 3.
- Structural determinants for generating centromeric chromatin.
Black BE, Foltz DR, Chakravarthy S, Luger K, Woods VL Jr, Cleveland DW.Nature. 2004 Jul 29;430(6999):578-82.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CENPA polyclonal antibody (Cat # PAB18324).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 1058
- Protein Accession#:
- P49450
- Gene Name:
- CENPA
- Gene Alias:
- CENP-A
- Gene Description:
- centromere protein A
- Omim ID:
- 117139
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000122589,centromere protein A, 17kDa