重组人粒细胞巨噬细胞集落刺激因子(Human GM-CSF)
产品名称: 重组人粒细胞巨噬细胞集落刺激因子(Human GM-CSF)
英文名称: Recombined Human GM-CSF
产品编号: SK-50
产品价格: 0
产品产地: China
品牌商标: Skoda
更新时间: 2023-09-19T17:40:47
使用范围: null
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重组人粒细胞巨噬细胞集落刺激因子(rhGM-CSF)作用于造血祖细胞,促进其增殖和分化,其重要作用是刺激粒、单核巨噬细胞成熟,促进成熟细胞向外周血释放,并能促进巨噬细胞及噬酸性细胞的多种功能。
北京上海客户使用证明与IL-4联用活化DC细胞效果明显。
GM-CSF is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Monocytes exit the circulation and migrate into tissue, whereupon they mature into macrophages and dendritic cells. Thus, it is part of the immune/inflammatory cascade, by which activation of a small number of macrophages can rapidly lead to an increase in their numbers, a process crucial for fighting infection. The active form of the protein is found extracellularly as a homodimer