FITC标记的G蛋白偶联受体128抗体
产品名称： FITC标记的G蛋白偶联受体128抗体
英文名称： Anti-GPR128/FITC
产品编号： HZ-13517R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GPR128/FITC Conjugated antibody
FITC标记的G蛋白偶联受体128抗体
| 英文名称 | Anti-GPR128/FITC |
| 中文名称 | FITC标记的G蛋白偶联受体128抗体 |
| 别 名 | FLJ14454; G protein coupled receptor 128; GP128_HUMAN; Gpr128; Probable G-protein coupled receptor 128; GPCR GPR128. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | a |
| 抗体来源 | |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human G protein coupled receptor 128 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells. Function: Orphan receptor. Subcellular Location: Cell membrane. Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Database links: Entrez Gene: 84873 Human Omim: 612307 Human SwissProt: Q96K78 Human Unigene: 334511 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
G蛋白偶联受体(GPCRs)又称为7个跨膜(7TM)受体和7个螺旋受体，是与G蛋白(异三聚GTPases)相互作用，合成细胞内第二信使的蛋白家族，如二酰甘油、环腺苷酸、肌醇磷酸盐，以及D钙离子。其多样的生物学功能从视觉和嗅觉到神经和内分泌信号传导，涉及许多病理状况。G蛋白受体128(GPR128)是GCPR的分泌素家族成员，其N端结构域具有GPS结构域，可通过G蛋白的激活介导信号传导过程到细胞内部。GPR128代表一种同种异体肽，它可能参与T细胞介导的移植排斥反应，因为它能够刺激2.102T细胞。