FITC标记的CP2相关转录抑制因子1抗体
产品名称: FITC标记的CP2相关转录抑制因子1抗体
英文名称: Anti-CRTR1/FITC
产品编号: HZ-12593R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CRTR1/FITC Conjugated antibody
FITC标记的CP2相关转录抑制因子1抗体
英文名称 | Anti-CRTR1/FITC |
中文名称 | FITC标记的CP2相关转录抑制因子1抗体 |
别 名 | CP2 related transcriptional repressor 1; CP2-related transcriptional repressor 1; CRTR 1; CRTR-1; LBP 9; LBP9; TF2L1_HUMAN; TFCP2 L1; TFCP2L1; Transcription factor CP2 like 1; Transcription factor CP2 like protein 1; Transcription factor CP2-like protein 1; Transcription factor LBP 9; Transcription factor LBP-9; Transcription factor LBP9. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 转录调节因子 结合蛋白 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 55kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CRTR1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The long terminal repeat binding protein-1 (LBP-1) mammalian family of transcription factors are proteins that stimulate transcription in HeLa cells from the major late promoter of simian virus 40 in vitro. The two related human LBP-1 genes are TFCP2A, which encodes the alternatively spliced transcripts LBP-1a and LBP-1b, and TFCP2C, which encodes LBP-1c and LBP-1d. LBP-9, also designated transcription factor CP2-like 1 (TFCP2L1), is a protein of 479 amino acids. LBP-9 shows 83% sequence homology with LBP-1b and acts as a suppressor factor inhibiting the stimulation effect of LBP-1b. LBP-9 may regulate the P450scc reporter activity through the -155/-131 element. Function: Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Modulates the placental expression of CYP11A1. Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue. Similarity: Belongs to the grh/CP2 family. CP2 subfamily. Database links: Entrez Gene: 29842 Human Entrez Gene: 81879 Mouse Omim: 609785 Human SwissProt: Q9NZI6 Human SwissProt: Q3UNW5 Mouse Unigene: 156471 Human Unigene: 24621 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
长末端重复结合蛋白-1(LBP-1)哺乳动物转录因子家族是体外刺激猴病毒40主要晚期启动子HeLa细胞转录的蛋白质。两个相关的人类LBP-1基因是编码交替剪接的转录本LBP-1a和LBP-1b的TFCP2A和编码LBP-1c和LBP-1d的TFCP2C。LBP-9与LBP-1b有83%的序列同源性,是抑制LBP-1b刺激效应的抑制因子,LBP-9可能通过-155/-131元件调节P450scc报告活性。