重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A)

中文名称：重组人SMPDL3A(酸性鞘磷脂酶如磷酸二酯酶3A)
英文名称：Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a
产品规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu23-Tyr453在C端含有His标签。

SMPDL3A质量控制：＞95%(还原性SDS-PAGE)

SMPDL3A制剂：冻干品

SMPDL3A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SMPDL3A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SMPDL3A：
Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A ) is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases. 

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！