分子量:28.7 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human LYPD3, His Tag by the LAL method.

Buffer:PBS, pH7.4

生物活性:

产品特性:Human LYPD3, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 28.7 kDa. The predicted N-terminus is Leu 31. The reducing (R) protein migrates as 45-68 kDa in SDS-PAGE  due to glycosylation.

产品背景:Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 ,C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein,which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.