C4B monoclonal antibody (M01), clone 2E3
产品名称: C4B monoclonal antibody (M01), clone 2E3
英文名称: C4B monoclonal antibody (M01), clone 2E3
产品编号: H00000721-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant C4B.
- Immunogen:
- C4B (NP_000583, 1347 a.a. ~ 1446 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- NNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEG
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged C4B is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 721
- GeneBank Accession#:
- NM_000592
- Protein Accession#:
- NP_000583
- Gene Name:
- C4B
- Gene Alias:
- C4A,C4A13,C4A91,C4B1,C4B12,C4B2,C4B3,C4B5,C4F,CH,CO4,CPAMD3,FLJ60561,MGC164979
- Gene Description:
- complement component 4B (Chido blood group)
- Omim ID:
- 120820
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq
- Other Designations:
- Chido form of C4,OTTHUMP00000029269,basic C4,complement C4B1a,complement component 4B,complement component 4B (Childo blood group)
- Related Disease
- Adrenal Hyperplasia, Congenital
- Adrenal hyperplasia, congenital
- Alzheimer Disease
- Alzheimer disease
- Angina Pectoris
- Atherosclerosis
- Autistic Disorder
- Autoimmune Diseases
- Cardiovascular Diseases
- Cerebrovascular Disorders
- Coronary Artery Disease
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Lupus Erythematosus, Systemic
- Metabolic Syndrome X
- Myocardial Infarction
- Neoplasms