Anti-TMEM74/FITC Conjugated抗体
产品名称： Anti-TMEM74/FITC Conjugated抗体
英文名称： Anti-TMEM74/FITC
产品编号： YB--9922R-FITC
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
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Anti-TMEM74/FITC Conjugated抗体
| 产品编号 | YB-9922R-FITC |
| 英文名称 | Anti-TMEM74/FITC |
| 中文名称 | FITC标记的跨膜蛋白74抗体 |
| 别 名 | TMEM 74; TMEM-74; NET36; HGNC; transmembrane protein 74; transmembrane protein-74; TMM74_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TMEM74 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: TMEM74 is a 305 amino acid protein encoded by a gene mapping to human chromosome 8. Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. Function: Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction. Subcellular Location: Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in heart, lung, and placenta. Similarity: Belongs to the TMEM74 family. Database links: Entrez Gene: 157753 Human Entrez Gene: 239408 Mouse Entrez Gene: 500864 Rat SwissProt: Q96NL1 Human SwissProt: Q8BQU7 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicationS |