MAPK3 polyclonal antibody
产品名称: MAPK3 polyclonal antibody
英文名称: MAPK3 polyclonal antibody
产品编号: PAB9870
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPK3.
- Immunogen:
- A synthetic peptide corresponding to amino acids 317-339 of human MAPK3.
- Host:
- Rabbit
- Reactivity:
- Bovine, Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (without Mg2+ and Ca2+), pH 7.3 (50% glycerol, 1 mg/mL BSA)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress.
Wang X, Grammatikakis N, Siganou A, Stevenson MA, Calderwood SK.J Biol Chem. 2004 Nov 19;279(47):49460-9. Epub 2004 Sep 10.
- 2.
- Prolonged nuclear retention of activated extracellular signal-regulated kinase 1/2 is required for hepatocyte growth factor-induced cell motility.
Tanimura S, Nomura K, Ozaki K, Tsujimoto M, Kondo T, Kohno M.J Biol Chem. 2002 Aug 2;277(31):28256-64. Epub 2002 May 24.
- 3.
- A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity.
Janulis M, Trakul N, Greene G, Schaefer EM, Lee JD, Rosner MR.Mol Cell Biol. 2001 Mar;21(6):2235-47.
- Entrez GeneID:
- 5595
- Gene Name:
- MAPK3
- Gene Alias:
- ERK1,HS44KDAP,HUMKER1A,MGC20180,P44ERK1,P44MAPK,PRKM3
- Gene Description:
- mitogen-activated protein kinase 3
- Omim ID:
- 601795
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000174538,OTTHUMP00000174540,extracellular signal-regulated kinase 1,extracellular signal-related kinase 1
- Interactome
- Gene Pathway
- Acute myeloid leukemia
- Adherens junction
- Alzheimer's disease
- Axon guidance
- B cell receptor signaling pathway
- Bladder cancer
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Dorso-ventral axis formation
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Gap junction
- Glioma
- GnRH signaling pathway
- Insulin signaling pathway
- Long-term depression
- Long-term potentiation
- MAPK signaling pathway
- Melanogenesis
- Melanoma
- mTOR signaling pathway
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prion diseases
- Prostate cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- T cell receptor signaling pathway
- TGF-beta signaling pathway
- Thyroid cancer
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- Vascular smooth muscle contraction
- VEGF signaling pathway