Alpha B Crystallin 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Alpha B Crystallin 抗体

Alpha B Crystallin 抗体

商家询价

产品名称： Alpha B Crystallin 抗体

英文名称： Alpha B Crystallin Antibody

产品编号： XY15808-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ALPHA B CRYSTALLIN 抗体

Applications
Tested Applications: ELISA, WB, IHC, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Human heart tissue, mouse heart tissue, mouse skeletal muscle tissue
Positive IP detected in Mouse heart tissue
Positive IHC detected in Human eye tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
 ALPHA B CRYSTALLIN 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 15808-1-AP;human heart tissuehuman heart tissue were subjected to SDS PAGE followed by western blot with 15808-1-AP(CRYAB antibody) at dilution of 1:500
  • 15808-1-AP;H-eyeImmunohistochemical of paraffin-embedded human eye using 15808-1-AP(CRYAB antibody) at dilution of 1:100 (under 10x lens)
  • 15808-1-AP;H-eyeImmunohistochemical of paraffin-embedded human eye using 15808-1-AP(CRYAB antibody) at dilution of 1:100 (under 40x lens)
  • 15808-1-AP;mouse heart tissueIP Result of anti-aB-Crystallin (IP:15808-1-AP, 3ug; Detection:15808-1-AP 1:500) with mouse heart tissue lysate 4000ug.
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information ALPHA B CRYSTALLIN 抗体
Immunogen: Alpha B Crystallin fusion protein ag8543 Full Name: Crystallin, alpha B
Caculated Molecular
Weight:		 175aa,20 kDa Observed Molecular 
Weight:		 20-22 kDa
GenbankNo BC007008 GeneID: 1410
Symbol CRYAB Synonyms Alpha B Crystallin, Alpha crystallin B chain, Alpha(B) crystallin, CRYA2, CRYAB, crystallin, alpha B, CTPP2, Heat shock protein beta 5, HSPB5, Rosenthal fiber component
Background

Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms (SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders. ALPHA B CRYSTALLIN 抗体

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