ANKRD20A1,锚蛋白重复结构域蛋白20A1抗体

产品编号HZ-9746R
英文名称ANKRD20A1
中文名称锚蛋白重复结构域蛋白20A1抗体
别 名A20A1_HUMAN; ANKRD20A; ANKRD20A1; Ankyrin repeat domain 20 family member A1; Ankyrin repeat domain 20A; Ankyrin repeat domain containing protein 20A1; Ankyrin repeat domain-containing protein 20A1; DKFZp434A171.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 免疫学 神经生物学
抗体来源Rabbit
ANKRD20A1,锚蛋白重复结构域蛋白20A1抗体克隆类型Polyclonal
交叉反应Human,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量94kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ANKRD20A1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ANKRD20A1,锚蛋白重复结构域蛋白20A1抗体PubMedPubMed
产品介绍background:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Post-translational modifications:

DISEASE:

ANKRD20A1,锚蛋白重复结构域蛋白20A1抗体Similarity:
Contains 5 ANK repeats.

Database links:
Entrez Gene: 84210 Human
SwissProt: Q5TYW2 Human
Unigene: 632671 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.