BTN2A1 + BTN2A2,嗜乳脂蛋白2亚型A1抗体

产品编号HZ-12909R
英文名称BTN2A1 + BTN2A2
中文名称嗜乳脂蛋白2亚型A1抗体
别 名BK14H9.1; BT2.1; BT2A1_HUMAN; BT2A2_HUMAN; BTF1; BTN2A1; Butyrophilin BTF1; Butyrophilin subfamily 2 member A1; CTA-14H9.1; DJ3E1.1.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 细胞凋亡 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Sheep,
BTN2A1 + BTN2A2,嗜乳脂蛋白2亚型A1抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-100 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量57kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BTN2A1 + BTN2A2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BTN2A1 + BTN2A2,嗜乳脂蛋白2亚型A1抗体PubMedPubMed
产品介绍background:
Butyrophilin is a glycoprotein that is specifically expressed on the apical surface of mammary epithelial cells during lactation and becomes incorporated as an integral protein into the membrane of the milk fat globule during the budding and secretion of fat droplets into milk. BTN2A1 (butyrophilin subfamily 2 member A1), also known as BTF1, is a 527 amino acid single-pass type I membrane B box protein that plays a role in fatty-acid, sterol and lipid metabolism. A member of the immunoglobulin superfamily and BTN/MOG family, BTN2A1 exists as three alternatively spliced isoforms found at high levels in brain, muscle, spleen, pancreas, bone marrow and small intestine. BTN2A1 is expressed at moderate levels in kidney, liver and lung, and is encoded by a gene that maps to human chromosome 6p22.1.

Subcellular Location:
Membrane; Single-pass type I membrane protein (By similarity).

Tissue Specificity:
Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.

BTN2A1 + BTN2A2,嗜乳脂蛋白2亚型A1抗体Similarity:
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 B30.2/SPRY domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID:
11120

Database links:
Entrez Gene: 11120 Human
Omim: 613590 Human
SwissProt: Q7KYR7 Human
Unigene: 159028 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.