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上海信裕生物科技有限公司
BRF2抗体

BRF2抗体

商家询价

产品名称: BRF2抗体

英文名称: BRF2Antibody

产品编号: XY12056-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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 BRF2抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 12056-1-AP;HT-1080 cellHT-1080 cells were subjected to SDS PAGE followed by western blot with 12056-1-AP(BRF2 antibody) at dilution of 1:300
Positive WB detected in HT-1080 cells, DU 145 cells
Recommended dilution WB : 1:200-1:2000
BRF2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen BRF2 fusion protein ag2686 Full name BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
Calculated molecular
weight
47 kDa Observed molecular 
weight
50-60 kDa
GenBank accession 
number
BC010648 Gene ID (NCBI) 55290
Gene symbol BRF2 Synonyms B related factor 2, BRF 2, BRF2, BRFU, FLJ11052, hBRFU, hTFIIIB50, TFIIIB50
BackgroundBRF2抗体

Human cells contain two types of RNA polymerase III transcription factor(TFIIIB), BRF1 and BRF2. BRF2,also named as BRFU, contains one TFIIB-type zinc finger. It is a general activator of RNA polymerase III transcription. It is a factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. BRF2 is recruited to type 3 promoters such as the human U6 snRNA promoter. It differs from BRF1-TFIIIB in that it contains the TFIIB-related factor BRF2 iinstead of BRF1 and its three components do not form a stable complex. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human BRF2. It recognizes a 50-60kd band in WB analysis.BRF2抗体

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