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上海信裕生物科技有限公司
BCO2抗体

BCO2抗体

商家询价

产品名称： BCO2抗体

英文名称： BCO2Antibody

产品编号： XY14324-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 BCO2抗体

Applications
In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Published applications WB Publications 3 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Mouse
Images
Prev12NextView more validation data
  • 14324-1-AP;L02 cellsL02 cells were subjected to SDS PAGE followed by western blot with 14324-1-AP(BCO2 antibody) at dilution of 1:800
  • 14324-1-AP;human liver cancerImmunohistochemical of paraffin-embedded human liver cancer using 14324-1-AP(BCO2 antibody) at dilution of 1:50 (under 10x lens)
  • 14324-1-AP;human liver cancerImmunohistochemical of paraffin-embedded human liver cancer using 14324-1-AP(BCO2 antibody) at dilution of 1:50 (under 40x lens)
  • 14324-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using BCO2 antibody 14324-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
Positive WB detected in L02 cells, human liver tissue, mouse liver tissue
Positive IHC detected in Human liver cancer tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200
 BCO2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen BCO2 fusion protein ag5590 Full name Beta-carotene oxygenase 2
Calculated molecular
weight		 66 kDa Observed molecular 
weight		 60-65kd
GenBank accession 
number		 BC041656 Gene ID (NCBI) 83875
Gene symbol BCO2 Synonyms B DIOX II, BCO2, Beta carotene dioxygenase 2, beta carotene oxygenase 2, FLJ34464
Background BCO2抗体

Beta,beta-carotene 9',10'-oxygenase (BCO2) catalyzes the asymmetric oxidative cleavage of beta-carotene in carotene metabolism.The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects. BCDO2 plays an important role in protecting against carotenoid-induced mitochondrial dysfunction and has a broader substrate specificity than previously recognized(PMID:22147584). This antibody detects the N-terminal of BCO2. BCO2抗体

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