BIRC3 polyclonal antibody
产品名称: BIRC3 polyclonal antibody
英文名称: BIRC3 polyclonal antibody
产品编号: PAB0253
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BIRC3.
- Immunogen:
- A synthetic peptide corresponding to amino acids 532-549 of human BIRC3.
- Sequence:
- KYIPTEDVSDLPVEEQLR
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In serum (0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of BIRC3 in various cancer cell lines. Using BIRC3 polyclonal antibody (Cat # PAB0253) at 1 : 2000.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of BIRC3 in paraffin-embedded formalin-fixed human mammary gland (female breast) using BIRC3 polyclonal antibody (Cat # PAB0253) at 1:2000.
A, normal breast tissue.
B, ductal carcinoma in situ (DCIS).
C. invasive neoplasia.
BIRC3 expressed increased sucessively with tumor progression.
Hematoxylin-eosin counterstain.
- Entrez GeneID:
- 330
- Gene Name:
- BIRC3
- Gene Alias:
- AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49
- Gene Description:
- baculoviral IAP repeat-containing 3
- Omim ID:
- 601721
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
- Other Designations:
- TNFR2-TRAF signaling complex protein,apoptosis inhibitor 2,baculoviral IAP repeat-containing protein 3,inhibitor of apoptosis protein 1,mammalian IAP homolog C