LASS5 polyclonal antibody
产品名称： LASS5 polyclonal antibody
英文名称： LASS5 polyclonal antibody
产品编号： PAB13440
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LASS5.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 18 amino acids of human LASS5.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- siRNA-Mediated Down-regulation of Ceramide Synthase 1 Leads to Apoptotic Resistance in Human Head and Neck Squamous Carcinoma Cells after Photodynamic Therapy.
Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI.Anticancer Res. 2012 Jul;32(7):2479-85.
- 2.
- Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI.Anticancer Res. 2012 Mar;32(3):753-60.
- 3.
- Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity.
Spassieva S, Seo JG, Jiang JC, Bielawski J, Alvarez-Vasquez F, Jazwinski SM, Hannun YA, Obeid LM.J Biol Chem. 2006 Nov 10;281(45):33931-8. Epub 2006 Sep 1.
- 4.
- LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor.
Lahiri S, Futerman AH.J Biol Chem. 2005 Oct 7;280(40):33735-8. Epub 2005 Aug 12.
- 5.
- Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.
Riebeling C, Allegood JC, Wang E, Merrill AH Jr, Futerman AH.J Biol Chem. 2003 Oct 31;278(44):43452-9. Epub 2003 Aug 11.
