Apelin Receptor,血管紧缩素样蛋白1抗体

产品编号HZ-2430R
英文名称Apelin Receptor
中文名称血管紧缩素样蛋白1抗体
别 名AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号
抗体来源Rabbit
克隆类型Polyclonal
Apelin Receptor,血管紧缩素样蛋白1抗体交叉反应Human, Mouse, Rat, Dog, Rabbit,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Apelin receptor
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Apelin Receptor,血管紧缩素样蛋白1抗体PubMedPubMed
产品介绍background:
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq

Function:
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Apelin Receptor,血管紧缩素样蛋白1抗体Gene ID:
187

Database links:
Entrez Gene: 429337 Chicken
Entrez Gene: 615435 Cow
Entrez Gene: 187 Human
Entrez Gene: 23796 Mouse
Entrez Gene: 83518 Rat
Omim: 600052 Human
SwissProt: P35414 Human
SwissProt: Q9WV08 Mouse
SwissProt: Q9JHG3 Rat
Unigene: 438311 Human
Unigene: 29368 Mouse
Unigene: 7965 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.