CWH43,细胞壁合成蛋白43抗体

产品编号HZ-9959R
英文名称CWH43
中文名称细胞壁合成蛋白43抗体
别 名Cell wall biogenesis protein 43 C-terminal homolog; Cwh43; imds 60; PG2IP_HUMAN; PGAP2-interacting protein.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
CWH43,细胞壁合成蛋白43抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量79kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CWH43
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CWH43,细胞壁合成蛋白43抗体PubMedPubMed
产品介绍background:
Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The CWH43 gene product has been provisionally designated CWH43 pending further characterization.

Function:
Involved in lipid remodeling during GPI-anchor maturation (By similarity).

Subunit:
Interacts with PGAP2/FRAG1 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Similarity:
Belongs to the PGAP2IP family.

Database links:
UniProtKB/Swiss-Prot: Q9H720.2

CWH43,细胞壁合成蛋白43抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.