ALCAM抗体
Applications
| Tested Applications: |
ELISA, IHC, WB |
| Specificity Reaction: |
Human; Other species are not tested.Please decide the specificity by homology |
| Positive WB detected in |
Human liver tissue |
| Positive IHC detected in |
Human breast cancer tissue, human colon cancer tissue |
| Recommended dilution |
WB : 1:200-1:2000
IHC : 1:20-1:200 |
ALCAM抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
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human liver tissue were subjected to SDS PAGE followed by western blot with 21972-1-AP(ALCAM antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human breast cancer using 21972-1-AP(ALCAM antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human breast cancer using 21972-1-AP(ALCAM antibody) at dilution of 1:50 (under 40x lens)
Product Information ALCAM抗体
| Source: |
Rabbit |
Purify: |
Antigen affinity purification |
| IsoType: |
IgG |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
| Immunogen: |
ALCAM fusion protein ag16892 |
Full Name: |
Activated leukocyte cell adhesion molecule |
Caculated Molecular
Weight: |
583aa,65 kDa |
Observed Molecular
Weight: |
110 kDa |
| GenbankNo |
BC137097 |
GeneID: |
214 |
| Symbol |
ALCAM |
Synonyms |
ALCAM, CD166, CD166 antigen, FLJ38514, MEMD |
Background
|
Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues. Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759). ALCAM抗体
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