Ermin,Ermin蛋白抗体

产品编号HZ-14626R
英文名称Ermin
中文名称Ermin蛋白抗体
别 名ERMN; ERM like protein; Ermin; ERMIN_HUMAN; ermin, ERM-like protein; JN; Juxtanodin; KIAA1189.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 结合蛋白 细胞类型标志物 细胞骨架
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit, Sheep,
Ermin,Ermin蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Ermin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Ermin,Ermin蛋白抗体PubMedPubMed
产品介绍background:
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

Function:
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity).

Subunit:
Binds actin (By similarity).

Subcellular Location:
Cytoplasm; cytoskeleton

Tissue Specificity:
Highly expressed in adult and fetal brain. Expressed at intermediate levels in the lung and liver.

Post-translational modifications:

Ermin,Ermin蛋白抗体DISEASE:

Gene ID:
57471

Database links:
Entrez Gene: 57471 Human
Omim: 610072 Human
SwissProt: Q8TAM6 Human
Unigene: 443894 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.