PER1 Pre-design Chimera RNAi
产品名称： PER1 Pre-design Chimera RNAi
英文名称： PER1 Pre-design Chimera RNAi
产品编号： H00005187-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Homo sapiens period homolog 1 (Drosophila) (PER1), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_002616
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 5187
- Gene Name:
- PER1
- Gene Alias:
- MGC88021,PER,RIGUI,hPER
- Gene Description:
- period homolog 1 (Drosophila)
- Omim ID:
- 602260
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described. [provided by RefSeq
- Other Designations:
- Period, drosophila, homolog of,circadian pacemaker protein RIGUI,period 1
- Gene Pathway
- Related Disease
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Bipolar Disorder
- Breast cancer
- Breast Neoplasms
- Chronobiology Disorders
- Cocaine-Related Disorders
- Depressive Disorder
- Depressive Disorder, Major
- Genetic Predisposition to Disease
- Mood Disorders
- NARP
- Ovarian cancer
- Paranoid Disorders
- Prostate cancer
- Prostatic Neoplasms
- Psychiatric Status Rating Scales
- Psychotic Disorders
- Schizophrenia