FRMD5,FRMD5蛋白抗体

产品编号HZ-8237R
英文名称FRMD5
中文名称FRMD5蛋白抗体
别 名FERM domain containing 5; FERM domain-containing protein 5; FLJ41022; FRMD5; FRMD5_HUMAN; MGC14161.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 通道蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
FRMD5,FRMD5蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量65kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FRMD5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FRMD5,FRMD5蛋白抗体PubMedPubMed
产品介绍background:
FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD5 (FERM domain-containing protein 5) is a 570 amino acid single-pass membrane protein that contains one FERM domain and exists as two alternatively spliced isoforms. The gene encoding FRMD5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Similarity:
Contains 1 FERM domain.

Gene ID:
84978

FRMD5,FRMD5蛋白抗体Database links:
Entrez Gene: 84978 Human
Entrez Gene: 228564 Mouse
Entrez Gene: 311362 Rat
SwissProt: Q7Z6J6 Human
SwissProt: Q6P5H6 Mouse
Unigene: 578544 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片	Sample:  lane1:HepG2 (human)cell Lysate at 40 ug lane2:U937 (human)cell Lysate at 40 ug Primary: Anti-FRMD5 (HZ-8237R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 65 kD Observed band size: 65 kD