EIF1B,真核翻译起始因子1B抗体

产品编号HZ-14532R
英文名称EIF1B
中文名称真核翻译起始因子1B抗体
别 名EIF1B; EIF1B_HUMAN; Eukaryotic translation initiation factor 1b; Protein translation factor SUI1 homolog GC20.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 转运蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Horse,
EIF1B,真核翻译起始因子1B抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量13kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EIF1B
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EIF1B,真核翻译起始因子1B抗体PubMedPubMed
产品介绍background:
In mammalian cells, translation is controlled at the level of polypeptide chain initiation by initiation factors. Eukaryotic translation initiation factor 1 (eIF1) is crucial for the scanning process in vitro. During the scanning process, eIF1 is a component of a complex involved in recognition of the initiator codon. Translation is also initiated by the role of eIF1 in regulating the activity of ribosomal subunits 43S, 48S and 40S. eIF1 enables 43S ribosomal complexes to discern between cognate and near-cognate initiation codons, sensing the nucleotide content of initiation codons. It is also a promotor, along with eukar-yotic translation initiation factor 1A (eIF1A), for assembly of 48S ribosomal complexes at the initiation codon of a conventional capped mRNA. In addition, eIF1 and eIF1A, together with eukaryotic translation initiation factor 5 (eIF5), function in the formation of stable 40S ribosomal preinitiation complexes.

Function:
Probably involved in translation.

Similarity:
Belongs to the SUI1 family.

Gene ID:
10289

Database links:
Entrez Gene: 10289 Human
SwissProt: O60739 Human
Unigene: 315230 Human

EIF1B,真核翻译起始因子1B抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.