CIAPIN1,细胞因子诱导凋亡抑制因子1抗体

产品编号HZ-5764R
英文名称CIAPIN1
中文名称细胞因子诱导凋亡抑制因子1
别 名Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow,
CIAPIN1,细胞因子诱导凋亡抑制因子1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CIAPIN1 (101-200aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CIAPIN1,细胞因子诱导凋亡抑制因子1抗体PubMedPubMed
产品介绍background:
CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.

Function:
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Similarity:
Belongs to the anamorsin family.

Database links:
UniProtKB/Swiss-Prot: Q6FI81.2

CIAPIN1,细胞因子诱导凋亡抑制因子1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.