FITC标记的信号转导相关蛋白3抗体
产品名称： FITC标记的信号转导相关蛋白3抗体
英文名称： Anti-KHDRBS3/FITC
产品编号： HZ-16956R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KHDRBS3/FITC Conjugated antibody
FITC标记的信号转导相关蛋白3抗体
| 英文名称 | Anti-KHDRBS3/FITC |
| 中文名称 | FITC标记的信号转导相关蛋白3抗体 |
| 别 名 | Etle; etoile; KH domain containing RNA binding signal transduction associated 3; KH domain containing RNA binding signal transduction associated protein 3; KH domain-containing; KHDR3_HUMAN; Khdrbs3; RNA binding protein T Star; RNA-binding; RNA-binding protein T-Star; SALP; Sam68 like mammalian protein 2; Sam68 like phosphotyrosine protein; Sam68 like phosphotyrosine protein T STAR; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; signal transduction-associated protein 3; SLM 2; SLM-2; SLM2; T STAR; TSTAR. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KHDRBS3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Function: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved vitro. Subunit: Self-associates to form homooligomers. Subcellular Location: Nucleus. Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one. Tissue Specificity: Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis. Post-translational modifications: Phosphorylated on tyrosine residues. Isoform 1 C-terminal region is tyrosine-rich, but isoform 2 lacking this C-terminal region is also tyrosine-phosphorylated. Similarity: Belongs to the KHDRBS family. Contains 1 KH domain. Database links: Entrez Gene: 10656 Human Entrez Gene: 13992 Mouse Entrez Gene: 64015 Rat Omim: 610421 Human SwissProt: O75525 Human SwissProt: Q9R226 Mouse SwissProt: Q9JLP1 Rat Unigene: 444558 Human Unigene: 17964 Mouse Unigene: 54682 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
RNA结合蛋白，在起着作用的选择性剪接的调控和影响mRNA剪接位点的选择和外显子包。可能作为细胞生长的负调控因子发挥作用。抑制细胞增殖。涉及血管内皮生长因子的剪接位点选择。诱导增加浓度依赖性结合CD44 mRNA前体的外显子的直接结合嘌呤丰富的外显子增强子。酪氨酸激酶PTK6下调RNA结合能力。涉及HIV-1基因表达的转录后调控。