FITC标记的N-乙酰神经氨酸合酶抗体
产品名称： FITC标记的N-乙酰神经氨酸合酶抗体
英文名称： Anti-NANS/FITC
产品编号： HZ-19009R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NANS/FITC Conjugated antibody
FITC标记的N-乙酰神经氨酸合酶抗体
| 英文名称 | Anti-NANS/FITC |
| 中文名称 | FITC标记的N-乙酰神经氨酸合酶抗体 |
| 别 名 | EC 2.5.1.56; EC 2.5.1.57; N acetylneuraminate 9 phosphate synthase; N acetylneuraminate synthase; N acetylneuraminic acid phosphate synthase; N acetylneuraminic acid synthase; N-acetylneuraminate synthase; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase; NANS; OTTHUMP00000021769; SAS; Sialic acid phosphate synthase; Sialic acid synthase; SIAS_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NANS |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008] Function: Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. Tissue Specificity: Ubiquitous. Similarity: Contains 1 AFP-like domain. Database links: Entrez Gene: 540602 Cow Entrez Gene: 54187 Human Entrez Gene: 94181 Mouse Entrez Gene: 298071 Rat Omim: 605202 Human SwissProt: Q9NR45 Human Unigene: 522310 Human Unigene: 665191 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一种在唾液酸生物合成途径中发挥作用的酶。在体外，编码蛋白使用N-乙酰甘露糖胺6-磷酸和甘露糖6-磷酸作为底物分别产生N-乙酰神经氨酸和2-酮-3-脱氧-D-甘油-D-半乳糖-壬酸(KDN)的磷酸化形式，然而，它对NY5AC磷酸盐产品。在昆虫细胞中，这种基因的表达导致NY5AC和KDN的产生。该基因与大肠杆菌唾液酸合成酶基因neuB有关，在大肠杆菌neuB阴性突变株中可部分恢复唾液酸合成酶活性。[ RefSeq，JUL 2008 ]