Anti-CCDC52抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-CCDC52抗体

Anti-CCDC52抗体

商家询价

产品名称: Anti-CCDC52抗体

英文名称: CCDC52

产品编号: YB--7989R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-CCDC52抗体

产品编号 YB-7989R
英文名称 CCDC52
中文名称 卷曲螺旋结构域蛋白52抗体
别    名 Coiled coil domain containing protein 52; Coiled-coil domain-containing protein 52; FLJ26064; FLJ44949; SPICE_HUMAN; spice1; Spindle and centriole-associated protein 1; Spindle and centriole-associated protein.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Rabbit, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 96kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCDC52:51-140/855 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. The gene encoding CCDC52 (Coiled-coil domain-containing protein 52), a 855 amino acid protein, exists on human chromosome 3.

Function:
Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Subunit:
Interacts with CEP120

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. 

SWISS:
Q8N0Z3

Gene ID:
152185

Database links:

Entrez Gene: 152185 Human

Omim: 613447 Human

SwissProt: Q8N0Z3 Human

Unigene: 477144 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.