DCL-1,C型凝集素受体CLEC13A抗体

产品编号HZ-13760R
英文名称DCL-1
中文名称C型凝集素受体CLEC13A抗体
别 名CD302; CLEC13A; DCL1; C-type lectin domain family 13 member A; C-type lectin BIMLEC; CD302_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 细胞粘附分子 细胞表面分子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Horse, Rabbit,
DCL-1,C型凝集素受体CLEC13A抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量26kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DCL-1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
DCL-1,C型凝集素受体CLEC13A抗体PubMedPubMed
产品介绍background:
DCL-1 is a 232 amino acid single-pass type I membrane protein involved in endocytosis, phagocytosis and cell adhesion and migration. A C-type lectin receptor, DCL-1 is widely expressed with highest levels found in peripheral blood, myeloid and B lymphoid cell lines, liver, ovary and lung. DCL-1 undergoes alternative splicing to produce three isoforms designated DCL-1 isoform 1, isoform 2 (also known as fusion protein variant V34-2) and isoform 3 (also designated fusion protein variant V33-2). DCL-1 isoforms 2 and 3 are produced in malignant lympoma cells, known as Hodgkin and Reed-Sternberg (HRS) cells. DCL-1 contains one C-type lectin domain and is encoded by a gene that maps to human chromosome 2q24.2. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Function:
Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

Subcellular Location:
Membrane.

DCL-1,C型凝集素受体CLEC13A抗体Similarity:
Contains 1 C-type lectin domain.

Gene ID:
9936

Database links:
Entrez Gene: 9936 Human
Entrez Gene: 66205 Mouse
Entrez Gene: 295629 Rat
Omim: 612246 Human
SwissProt: Q8IX05 Human
SwissProt: Q9DCG2 Mouse
SwissProt: Q5FVR3 Rat
Unigene: 130014 Human
Unigene: 674903 Human
Unigene: 227281 Mouse
Unigene: 98436 Rat

DCL-1,C型凝集素受体CLEC13A抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.