ARHGDIB 抗体
Applications
| Tested Applications: |
ELISA, IHC, WB, IP |
| Cited applications |
WB |
| Specificity Reaction: |
Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology |
| Cited species |
Human |
| Positive WB detected in |
Jurkat cells, HL-60 cells, K-562 cells, Raji cells, rat spleen tissue |
| Positive IP detected in |
Raji cells |
| Positive IHC detected in |
Human stomach cancer tissue |
| Recommended dilution |
WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200 |
ARHGDIB 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12Next
Jurkat cells were subjected to SDS PAGE followed by western blot with 16122-1-AP(ARHGDIB antibody) at dilution of 1:1000
IP Result of anti-ARHGDIB (IP:16122-1-AP, 4ug; Detection:16122-1-AP 1:1000) with Raji cells lysate 2000ug.
Immunohistochemical of paraffin-embedded human stomach cancer using 16122-1-AP(ARHGDIB antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human stomach cancer using 16122-1-AP(ARHGDIB antibody) at dilution of 1:100 (under 40x lens)
Product Information ARHGDIB 抗体
| Source: |
Rabbit |
Purify: |
Antigen affinity purification |
| IsoType: |
IgG |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
| Immunogen: |
ARHGDIB fusion protein ag9078 |
Full Name: |
Rho GDP dissociation inhibitor (GDI) beta |
Caculated Molecular
Weight: |
201aa,23 kDa |
Observed Molecular
Weight: |
27 kDa |
| GenbankNo |
BC009200 |
GeneID: |
397 |
| Symbol |
ARHGDIB |
Synonyms |
ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2 |
Background
|
ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer. ARHGDIB 抗体
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