ITGA2B/ITGB3 monoclonal antibody, clone 700
产品名称: ITGA2B/ITGB3 monoclonal antibody, clone 700
英文名称: ITGA2B/ITGB3 monoclonal antibody, clone 700
产品编号: MAB6389
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against ITGA2B/ITGB3.
- Immunogen:
- Native from human platelets suspension.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Under reducing conditions this antibody will bind against the human ITGA2B/ITGB3 complex.
- Form:
- Lyophilized
- Isotype:
- IgG1, kappa
- Storage Buffer:
- Lyophilized from 10 mM PBS, pH 7.2
- Storage Instruction:
- Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (10-20 ug/mL)
ELISA (100ul of 108 washed platelets)
The optimal working dilution should be determined by the end user.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 3674
- Gene Name:
- ITGA2B
- Gene Alias:
- CD41,CD41B,GP2B,GPIIb,GTA,HPA3
- Gene Description:
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq
- Other Designations:
- integrin alpha 2b,platelet fibrinogen receptor, alpha subunit,platelet-specific antigen BAK
- Entrez GeneID:
- 3690
- Gene Name:
- ITGB3
- Gene Alias:
- CD61,GP3A,GPIIIa
- Gene Description:
- integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
- Omim ID:
- 173470
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
- Other Designations:
- integrin beta chain, beta 3,platelet glycoprotein IIIa