重组人血小板衍生生长因子BB
产品名称： 重组人血小板衍生生长因子BB
英文名称： Recombinant Human PDGF-BB Protein
产品编号： 91605ES05
产品价格： 535.00
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2024-04-03T16:28
使用范围： null
| 规格 | 价格 |
| 2μg | 535.0 |
| 10 μg | 1855.0 |
| 50 μg | 4635.0 |
| 100 μg | 6955.0 |
| 500 μg | 17385.0 |
- 联系人 : 李自转
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Product Description
Platelet-derived growth factor (PDGF) was discovered as a major mitogenic factor present in serum but absent from plasma. In vitro, PDGF-BB stimulated MAP kinase activity and cell motility of isolated lymphatic endothelial cells. In vivo, PDGF-BB potently induced growth of lymphatic vessels. Expression of PDGF-BB in murine fibrosarcoma cells induced tumor lymphangiogenesis, leading to enhanced metastasis in lymph nodes. The PDGF signaling system contributes to and vascular remodeling. Growth factors such as PDGF exert potent effects on wound healing including the regeneration of tooth-supporting structures.
Product Properties
Synonyms
Becaplermin, ODGF, PDGF-2, PDGFBB, PDGF-BB
Accession
P01127
GeneID
5155
Source
E.coli-derived human PDGF-BB protein, Ser82-Thr190, with an N-terminal Met.
Molecular Weight
Approximately 24.8 kDa
AA Sequence
MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 97 % by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 3 ng/ml, corresponding to a specific activity of > 3.3 × 105 IU/mg.
Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
- For your safety and health, please wear lab coats and disposable gloves for operation.
- For research use only.
HB240307
HB240307