Anti-IGF1R Polyclonal Antibody
产品名称: Anti-IGF1R Polyclonal Antibody
英文名称: CD221;IGFIR;IGFR;JTK13
产品编号: K001621P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IHC IF
北京索莱宝科技有限公司--实验室产品
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This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.