C3 / C3b / C3c 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
C3 / C3b / C3c 抗体

C3 / C3b / C3c 抗体

商家询价

产品名称： C3 / C3b / C3c 抗体

英文名称： C3 / C3b / C3c Antibody

产品编号： XY: 21337-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 C3 / C3B / C3C 抗体

Applications
In-house applications ELISA, WB, IP, IHC     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev12NextView more validation data
  • 21337-1-AP;human blood tissuehuman blood tissue were subjected to SDS PAGE followed by western blot with 21337-1-AP(C3 antibody) at dilution of 1:1000
  • 21337-1-AP;human plasma tissueIP Result of anti-C3 (IP:21337-1-AP, 4ug; Detection:21337-1-AP 1:1000) with human plasma tissue lysate 4000ug.
  • 21337-1-AP;human liver tissueImmunohistochemistry of paraffin-embedded human liver tissue slide using 21337-1-AP( C3 Antibody) at dilution of 1:100 (under 10x lens).
  • 21337-1-AP;human liver tissueImmunohistochemistry of paraffin-embedded human liver tissue slide using 21337-1-AP( C3 Antibody) at dilution of 1:100 (under 40x lens).
Positive WB detected in Human blood tissue
Positive IP detected in Human plasma tissue
Positive IHC detected in Human liver tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:50-1:500
 C3 / C3B / C3C 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen C3 / C3b / C3c fusion protein ag15537 Full name Complement component 3
Calculated molecular
weight		 1663aa,187 kDa Observed molecular 
weight		 115 kDa
GenBank accession 
number		 BC150179 Gene ID (NCBI) 718
Gene symbol C3 Synonyms ARMD9, ASP, C3, C3b, C3c, Complement C3, complement component 3, CPAMD1
Background C3 / C3B / C3C 抗体

The complement system is an important effector which bridges the innate and adaptive immune systems (PMID: 20010915). The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways (PMID: 11414361). Human C3, composed of α and β chains (115 and 75 kDa, respectively), is cleaved into C3a and C3b by C3 convertase. C3b is further cleaved into iC3b, C3c, C3dg and C3f. This antibody raised against 1314-1663 aa of human C3 protein recognize C3 alpha chain, C3b alpha' chain, and C3c alpha' chain fragment 2. C3 / C3B / C3C 抗体

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