MAML1 polyclonal antibody
产品名称： MAML1 polyclonal antibody
英文名称： MAML1 polyclonal antibody
产品编号： PAB6471
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of MAML1.
- Immunogen:
- A synthetic peptide corresponding to N terminus of human MAML1.
- Sequence:
- VLPTCPMAEFALPR
- Host:
- Goat
- Theoretical MW (kDa):
- 108
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:128000)
Western blot (0.1-0.3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-3.8 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.
Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffin JD.Nat Genet. 2000 Dec;26(4):484-9.
- Applications
- Western Blot (Tissue lysate)
- MAML1 polyclonal antibody (Cat # PAB6471) (0.1 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 9794
- Protein Accession#:
- NP_055572
- Gene Name:
- MAML1
- Gene Alias:
- KIAA0200,Mam-1,Mam1
- Gene Description:
- mastermind-like 1 (Drosophila)
- Omim ID:
- 605424
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq
- Other Designations:
- mastermind homolog,mastermind-like 1
- Gene Pathway
- Related Disease