Anti-PSCD1/Cytohesin 1/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-PSCD1/Cytohesin 1/FITC Conjugated抗体

Anti-PSCD1/Cytohesin 1/FITC Conjugated抗体

商家询价

产品名称： Anti-PSCD1/Cytohesin 1/FITC Conjugated抗体

英文名称： Anti-PSCD1/Cytohesin 1/FITC

产品编号： YB--6707R-FITC

产品价格： null

产品产地： 中国/美国

品牌商标： Ybscience

更新时间： 2023-08-17T10:29:50

使用范围： 科研使用

上海钰博生物科技有限公司
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 Anti-PSCD1/Cytohesin 1/FITC Conjugated抗体

产品编号 YB-6707R-FITC
英文名称 Anti-PSCD1/Cytohesin 1/FITC
中文名称 FITC标记的胞粘蛋白1抗体
别    名 SEC7 and coiled-coil domain-containing protein 1; B2 1; CLM1; CTH 1; CYH1_HUMAN; CYTH1; CYTIP; Cytoadhesin 1; Cytohesin-1; Homolog of secretory protein SEC7; mSec7 1; PH; PH, SEC7 and coiled-coil domain containing protein 1; Pleckstrin homology Sec7 and coiled/coil domains 1; Pleckstrin homology Sec7 and coiled/coil domains protein 1; PSCD1; Sec7; SEC7 homolog A; SEC7 homolog B2 1; SEC7 homolog B2-1; SEC7, yeast, homolog of; Sec7a.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PSCD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Cytohesin 1 is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. Cytohesin 1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.

Function:
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF through replacement of GDP with GTP.

Subunit:
Interacts with TRIM23 and CYTIP.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 PH domain. 
Contains 1 SEC7 domain.

Database links:

Entrez Gene: 9267 Human

Entrez Gene: 19157 Mouse

Entrez Gene: 116691 Rat

Omim: 182115 Human

SwissProt: Q15438 Human

SwissProt: Q9QX11 Mouse

SwissProt: P97694 Rat

Unigene: 191215 Human

Unigene: 86413 Mouse

Unigene: 10672 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications