NAMPT monoclonal antibody, clone 4D5
产品名称： NAMPT monoclonal antibody, clone 4D5
英文名称： NAMPT monoclonal antibody, clone 4D5
产品编号： MAB1122
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant NAMPT.
- Immunogen:
- Recombinant protein corresponding to full length human NAMPT.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1000-1:3000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity.
Stephens JM, Vidal-Puig AJ.Curr Opin Lipidol. 2006 Apr;17(2):128-31.
- 2.
- Medicine. Visfatin: a new adipokine.
Hug C, Lodish HF.Science. 2005 Jan 21;307(5708):366-7. Epub 2004 Dec 16.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of cell lysates of 293T (30 ug) were resolved by SDS - PAGE , transferred to NC membrane and probed with NAMPT monoclonal antibody , clone 4D5 (1 : 1000) (Cat # MAB1122). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 10135
- GeneBank Accession#:
- NM_005746
- Protein Accession#:
- NP_005737
- Gene Name:
- NAMPT
- Gene Alias:
- 1110035O14Rik,DKFZp666B131,MGC117256,PBEF,PBEF1,VF,VISFATIN
- Gene Description:
- nicotinamide phosphoribosyltransferase
- Omim ID:
- 608764
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10. [provided by RefSeq
- Other Designations:
- NAmPRTase,pre-B cell-enhancing factor,pre-B-cell colony enhancing factor 1
- Gene Pathway