EF-CBP2,突触结合蛋白2抗体

产品编号HZ-9016R
英文名称EF-CBP2
中文名称突触结合蛋白2抗体
别 名EF hand calcium binding protein 2; EF-hand calcium-binding protein 2; N-terminal EF-hand calcium-binding protein 2; NECA2_HUMAN; Necab2; EFCBP2; EF CBP2; Neuronal calcium binding protein 2; Neuronal calcium-binding protein 2; Stip 2; Stip-2; Stip2; Synaptotagmin interacting protein 2; Synaptotagmin-interacting protein 2.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 神经生物学 结合蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow,
EF-CBP2,突触结合蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量43kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EF-CBP2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EF-CBP2,突触结合蛋白2抗体PubMedPubMed
产品介绍background:
Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Subcellular Location:
Cytoplasm (By similarity).

Tissue Specificity:
Expressed in brain

Similarity:
Contains 1 ABM domain.
Contains 2 EF-hand domains.

Database links:
Entrez Gene: 54550 Human
SwissProt: Q7Z6G3 Human
Unigene: 140950 Human

EF-CBP2,突触结合蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.