ALDH3A1 (Human) Recombinant Protein
产品名称: ALDH3A1 (Human) Recombinant Protein
英文名称: ALDH3A1 (Human) Recombinant Protein
产品编号: P3496
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ALDH3A1 (AAH04370, 1 a.a. - 453 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
- Sequence:
- MGSSHHHHHHSSGLVPRGSHMSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
- Theoretical MW (kDa):
- 52.5
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purification:
- Conventional Chromatography
- Concentration:
- 0.5 mg/mL
- Purity:
- > 95% by SDS-PAGE
- Activity:
- Specific activity is < 1 units/mL and was obtained by measuring the increase of NADP in absorbance at 340 nm resulting from the reduction of NAD. One unit will oxidize 1.0 umole of acetaldehyde to acetic acid per minute at pH 8.0 at 25°C in the pre
- Storage Buffer:
- In 20 mM Tris-HCl, 0.1M NaCl, pH 8.0 (10% glycerol)
- Storage Instruction:
- Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 3 ug protein in 15% SDS-PAGE
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 218
- Protein Accession#:
- AAH04370
- Gene Name:
- ALDH3A1
- Gene Alias:
- ALDH3,ALDHIII,MGC10406
- Gene Description:
- aldehyde dehydrogenase 3 family, memberA1
- Omim ID:
- 100660
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
- Other Designations:
- aldehyde dehydrogenase 3A1,aldehyde dehydrogenase isozyme 3,aldehyde dehydrogenase type III,aldehyde dehydrogenase, dimeric NADP-preferring,stomach aldehyde dehydrogenase
- Related Disease
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Ductal, Breast
- Drug Toxicity
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- NARP
- Neoplasms
- Neoplasms, Germ Cell and Embryonal
- Ovarian cancer
- Ovarian Neoplasms
- Schizophrenia
- Schizophrenia, Paranoid
- Tobacco Use Disorder