分子量:95.3 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Rhesus macaque EGF R, Fc Tag by the LAL method.

Buffer:50 mM tris, 100 mM glycine, pH7.5

生物活性:

产品特性:Rhesus macaque EGF R, Fc Tag is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 95.3 kDa. The predicted N-terminus is Leu 25. The reducing (R) protein migrates as 130-140 kDa in SDS-PAGE  due to glycosylation.

产品背景:The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.