APOBEC3B抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
APOBEC3B抗体

APOBEC3B抗体

商家询价

产品名称： APOBEC3B抗体

英文名称： APOBEC3BAntibody

产品编号： XY14559-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 APOBEC3B抗体

Applications
In-house applications ELISA, IP, IHC, WB     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 14559-1-AP;MDA-MB-453s cellsMDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 14559-1-AP( APOBEC3B Antibody) at dilution of 1:300
  • 14559-1-AP;mouse spleen tissueIP Result of anti-APOBEC3B (IP:14559-1-AP, 4ug; Detection:14559-1-AP 1:500) with mouse spleen tissue lysate 4000ug.
  • 14559-1-AP;human breast cancer tissueImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using 14559-1-AP( APOBEC3B Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Positive WB detected in MDA-MB-453s cells, Transfected HEK-293 cells
Positive IP detected in Mouse spleen tissue
Positive IHC detected in Human breast cancer tissue
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:2000
IHC : 1:20-1:200
 APOBEC3B抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen APOBEC3B fusion protein ag6115 Full name Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Calculated molecular
weight		 46 kDa Observed molecular 
weight		 30 kDa
GenBank accession 
number		 BC053859 APOBEC3B抗体 Gene ID (NCBI) 9582
Gene symbol APOBEC3B Synonyms APOBEC1L, APOBEC3B, ARCD3, ARP4, bK150C2.2, DJ742C19.2, FLJ21201, Phorbolin 1 related protein, Phorbolin 2/3, PHRBNL
Background

The DNA cytosine deaminase APOBEC3B was identified recently as a source of DNA damage and mutagenesis in breast, head/neck, cervix, bladder, lung, ovary, and to lesser extents additional cancer types. This enzyme is also an effector protein in the innate immune response to virus infection. APOBEC3B has 3 isoforms produced by alternative splicing with the MW of 46, 29, 43 kDa. It can also exsit as a dimer and can interact with APOBEC3G. APOBEC3B抗体

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