FITC标记的松弛肽2/松弛素2抗体
产品名称： FITC标记的松弛肽2/松弛素2抗体
英文名称： Anti-Relaxin 2/FITC
产品编号： HZ-19835R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Relaxin 2/FITC Conjugated antibody
FITC标记的松弛肽2/松弛素2抗体
| 英文名称 | Anti-Relaxin 2/FITC |
| 中文名称 | FITC标记的松弛肽2/松弛素2抗体 |
| 别 名 | H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; REL2_HUMAN; Relaxin 2 (H2); Relaxin 2; Relaxin A chain; Relaxin H2; Relaxin, Ovarian, Of Pregnancy; RLN2; RLXH2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 生长因子和 |
| 抗体来源 | |
| 克隆类型 | |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Relaxin 2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013] Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. Subcellular Location: Secreted. Tissue Specificity: Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary. Similarity: Belongs to the insulin family. Database links: Entrez Gene: 6013 Human Entrez Gene: 6019 Human Entrez Gene: 25616 Rat Omim: 179740 Human SwissProt: P04090 Human SwissProt: P04808 Human SwissProt: P47932 Mouse SwissProt: P01347 Rat Unigene: 127032 Human Unigene: 368996 Human Unigene: 5033 Mouse Unigene: 9830 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
松弛素是已知的内分泌和自分泌/旁分泌，属于胰岛素基因超家族。在人类中有三个非等位基因松弛素基因，RLN1、RLN2和RLN3，其中RLN1和RLN2具有高序列同源性。该基因编码的蛋白被合成为单链多肽，但其活性形式由A链和B链组成，B链通过二硫键连接。松弛素是由卵巢产生的，它的作用是使哺乳动物的生殖系统成熟子宫颈，延长耻骨联合，抑制子宫收缩。它在增强精子活力、调节血压、控制心率、释放催产素和血管加压素方面可能还有其他作用。[ RefSeq，2013月1日]