CA I,碳酸酐酶1抗体

产品编号HZ-1592R
英文名称CA I
中文名称碳酸酐酶1抗体
别 名Carbonic anhydrase I; Carbonic Anhydrase-I; Carbonic Anhydrase 1; Carbonic anhydrase1; Carbonic anhydrase-1; JW0122; CA 1; CA1; CA I; CA-1; CAI; CAN; Car 1; Car1; Carbonate dehydratase I; Carbonic anhydrase 1; Carbonic anhydrase B; Carbonic dehydratase; ECK0125; yadF; CAH1_MOUSE.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 免疫学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Rabbit, Sheep,
CA I,碳酸酐酶1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
细胞定位细胞膜 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CA I
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CA I,碳酸酐酶1抗体PubMedPubMed
产品介绍background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq, Sep 2009]

Function:
Reversible hydration of carbon dioxide.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the alpha-carbonic anhydrase family.

Gene ID:
759

CA I,碳酸酐酶1抗体Database links:
Entrez Gene: 759 Human
Entrez Gene: 12346 Mouse
Entrez Gene: 310218 Rat
Omim: 114800 Human
SwissProt: P00915 Human
SwissProt: P13634 Mouse
SwissProt: B0BNN3 Rat
Unigene: 23118 Human
Unigene: 273195 Mouse
Unigene: 6854 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CA1(Carbonic anhydrase1)是红细胞的主要蛋白质成分之一,是一种重要的锌酶，对血液及组织起到维持酸碱平衡的作用，协助体内组织排除二氧化碳，碳酸酐酶I参与呼吸、钙化、酸碱平衡、骨吸收和各种体液形成的生理过程。