Anti-Nav1.1 mAb: ATTO 594 [S74-71]
产品名称： Anti-Nav1.1 mAb: ATTO 594 [S74-71]
英文名称： Nav1.1 Monoclonal Antibody: ATTO 594 [S74-71]
产品编号： SMC-376D-A594
产品价格： null
产品产地： 加拿大
品牌商标： StressMarq
更新时间： null
使用范围： WB, IHC, IP
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Voltage gated sodium channels initiate action potentials in neurons. Nav1.1 is abundant in the adult brain, and primarily localized in cell bodies. Mutations in the Nav1.1 channels cause generalized epilepsy with febrile seizures plus (GEFS+). Studies show that Nav1.1 channels also play a crucial role in the excitability of cerebellar Purkinje neurons, with major contributions to peak, persistent and resurgent forms of sodium current and to sustained action potential firing (3).