FITC标记的神经元突触膜胞外分泌调节蛋白4抗体
产品名称： FITC标记的神经元突触膜胞外分泌调节蛋白4抗体
英文名称： Anti-RIMS4/FITC
产品编号： HZ-11360R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-RIMS4/FITC Conjugated antibody
FITC标记的神经元突触膜胞外分泌调节蛋白4抗体
| 产品编号 | bs-11360R-FITC |
| 英文名称 | Anti-RIMS4/FITC |
| 中文名称 | FITC标记的神经元突触膜胞外分泌调节蛋白4抗体 |
| 别 名 | C20orf190; dJ781B1.3; Rab3-interacting molecule 4; regulating synaptic membrane exocytosis 4; Regulating synaptic membrane exocytosis protein 4; RIM 4; RIM4 gamma; Rims4; RIMS4_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RIMS4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis. Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins. Function: Regulates synaptic membrane exocytosis. Subunit: Binds PPFIA3 (By similarity). Does not bind RAB3. Subcellular Location: Cell junction; synapse. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 C2 domain. Database links: UniProtKB/Swiss-Prot: Q9NYW1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
RIM4（RAB 3相互作用分子4），也称为RIM4或调节突触膜胞吐蛋白4，是一种269氨基酸蛋白，定位于细胞连接并调节突触膜胞吐作用。RAB 3是Rab家族的神经/神经内分泌特异性成员，参与Ca2+调节的胞吐作用。RAB 3通过抑制分泌泡在质膜中的可释放池中的吸收而发挥抑制作用。RAB（RAB 3相互作用分子）是RAB 3蛋白的一个假定的效应蛋白，被认为通过与RAB 3和其他突触蛋白的相互作用调节中性粒细胞释放。