FITC标记的液泡蛋白分选蛋白36抗体
产品名称： FITC标记的液泡蛋白分选蛋白36抗体
英文名称： Anti-VPS36/FITC
产品编号： HZ-12773R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-VPS36/FITC Conjugated antibody
FITC标记的液泡蛋白分选蛋白36抗体
| 英文名称 | Anti-VPS36/FITC |
| 中文名称 | FITC标记的液泡蛋白分选蛋白36抗体 |
| 别 名 | C13orf9; CGI 145; EAP45; ELL associated protein of 45 kDa; ELL-associated protein of 45 kDa; ESCRT-II complex subunit VPS36; Vacuolar protein sorting associated protein 36; Vacuolar protein-sorting-associated protein 36; Vps36; VPS36_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 44kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VPS36 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A similar protein complex in rat is associated with RNA polymerase elongation factor II. [provided by RefSeq, Aug 2013] Function: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3. Subcellular Location: Cytoplasm. Endosome. Late endosome. Membrane. Nucleus. Colocalizes with ubiquitinated proteins on late endosomes. Recruited to the endosome membrane to participate in vesicle formation. Similarity: Belongs to the VPS36 family. Contains 1 GLUE domain. Database links: Entrez Gene: 418883 Chicken Entrez Gene: 511223 Cow Entrez Gene: 477292 Dog Entrez Gene: 51028 Human Entrez Gene: 70160 Mouse Entrez Gene: 290851 Rat Entrez Gene: 335810 Zebrafish Omim: 610903 Human SwissProt: A5PK00 Cow SwissProt: Q86VN1 Human SwissProt: Q91XD6 Mouse SwissProt: P0C0A2 Rat SwissProt: Q7ZVK4 Zebrafish Unigene: 109520 Human Unigene: 41453 Mouse Unigene: 474298 Mouse Unigene: 12707 Rat Unigene: 21065 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码一种蛋白质，它是转运II(ESCRT-II)所需的内体分选复合物的亚基。该蛋白复合物在胞内吞过程中对泛素化的膜蛋白进行分选。在大鼠中类似的蛋白复合物与RNA聚合酶延伸因子II相关。[ RefSeq，Aug 2013提供]