Anti-RASA2抗体
产品名称: Anti-RASA2抗体
英文名称: RASA2
产品编号: YB--6171R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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Anti-RASA2抗体
产品编号 | YB-6171R |
英文名称 | RASA2 |
中文名称 | RAS的GTP酶激活蛋白抗体 |
别 名 | GAP1M; GTPase activating protein of RAS; Ras GTPase activating protein 2; Ras GTPase-activating protein 2; RAS p21 protein activator 2; RASA2; RASA2_HUMAN; RASGAP. |
规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 肿瘤 细胞生物 染色质和核信号 细胞周期蛋白 细胞分化 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 96kDa |
细胞定位 | 细胞浆 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RASGAP:765-849/849 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008]. Function: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4). Subcellular Location: Cytoplasm. Cytoplasm, perinuclear region. Similarity: Contains 1 Btk-type zinc finger. Contains 2 C2 domains. Contains 1 PH domain. Contains 1 Ras-GAP domain. SWISS: Q15283 Gene ID: 5922 Database links: Entrez Gene: 5922 Human Entrez Gene: 114713 Mouse Entrez Gene: 25597 Rat Omim: 601589 Human SwissProt: Q15283 Human SwissProt: P58069 Mouse SwissProt: Q63713 Rat Unigene: 241548 Human Unigene: 655941 Human Unigene: 124502 Mouse Unigene: 161946 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |